What determines whether an axolotl will grow up to be male or female?

Axolotls have genetic sex-determination - a locus on an axolotl chromosome determines whether an axolotl is male or female.

In salamanders, the sex determining mechanism is referred to as ZZ/ZW and the heterogametic sex is female.

Fun Facts

Why is the axolotl genome so large?

As a group, salamanders have larger genomes than the other amphibians.

It doesn’t appear that the axolotl has more genes than other vertebrates (Smith et al., 2009).

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